Muscle laboratory
Senior physicians:
PD Dr. H. Tumani
Phone: 0731/177-5204
Email: hayrettin.tumani@rku.de
Staff:
Dr. H-J Gdynia
Phone: 0731 177-5225
Email: hans-juergen.gdynia@uni-ulm.de
Senior MTA:
Ms H. Mogel
Phone: 0731 177-1518
Fax: 0731 177-1519
A high percentage of myopathic disorders still requires a histological analysis of a tissue specimen taken from the skeletal muscle. As a sector of neurology, myopathic disorder diagnostics is therefore based around cellular examinations of the skeletal muscle.
Apart from standard histology (structural myopathies, inflammatory myopathies, i.e. polymyositis/dermatomyositis, inclusion body myositis, mitchondrial myopathies, disproportionate fibres, MADD, toxic myopathies, lipometabolic disorders, neurogenic muscular atrophy) we also offer immunohistochemistry for the following myopathic disorders:
- all limb girdle dystrophies open to diagnosis
- lymphocyte markers and superficial markers applicable to inflammatory myopathies (polymyositis, dermatomyositis)
- superficial markers applicable to muscular dystrophy of the Duchenne/Becker/Emery-Dreifuss type
- congenital muscular dystrophies
- glycogen metabolism disorders.
In cases requiring more detailed investigation, we collaborate with Friedrich-Baur-Institut in Munich and the muscle laboratory of Halle University Clinic.
To be able to properly handle the muscle material and to provide an efficient analysis, we need all clinical symptomatic details and must insist on quickly taking the muscle material to cryo-conservation.
Inquiries about the presence of a myositis are answered by returning preliminary histological results within 48h following biopsy to allow the appropriate therapeutic actions to be taken quickly.